Essential Dental Treatment (EDT) in Pregnant Women during the Second Trimester Is Not Associated with an Increased Risk of Serious Adverse Pregnancy Outcomes or Medical Events

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A total of 814 of 823 subjects initially enrolled in the OPT. Seven subjects were lost to follow-up and 2 subjects withdrew their consents. Excluded subjects were (1) women with multiple fetuses, (2) women requiring antibiotic prophylaxis before treatment, (3) women with a medical condition that precluded elective dental treatment, and (4) women who were likely to have fewer than 20 remaining teeth after treatment of moderate-to-severe caries, abscesses, or other nonperiodontal pathoses.


Essential dental treatment (EDT) between 13 and 21 weeks’ gestation.

Main Outcome Measure

Adverse pregnancy outcomes.

Main Results

EDT between 13 and 21 weeks’ gestation was not significantly associated with any adverse pregnancy outcome (P > .10).


EDT between 13 and 21 weeks’ gestation does not present a significant risk of any adverse medical or pregnancy outcome.

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