Most radiolucent jaw lesions are benign and resolve with proper diagnosis and treatment. However, a small percentage of radiolucent jaw lesions are malignant and more difficult to manage.Methods:
A biopsy of the radiolucent jaw lesion associated with swelling after nonsurgical root canal therapy was submitted.Results:
The lesion had the combined diagnosis of diffuse large B-cell lymphoma with cystic involvement. The patient has since undergone radiation and chemotherapy treatments. Recall appointments indicate healing of the lesion, and no other areas of lymphoma have been found.Conclusions:
The existence of a nonhealing radiolucent jaw lesion emphasizes the importance of an early, definitive diagnosis with biopsy.