Ultrasonographic evaluation of gallbladder functions in patients with irritable bowel syndrome

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The aim of the present study was to evaluate gallbladder function in irritable bowel syndrome (IBS) patients.


The functions of gallbladder were investigated every 30 min for 4 h. In addition, ejection fraction of the gallbladder was calculated from the fasting and post-prandial volumes.


In IBS patients and healthy controls, fasting gallbladder volumes were 19.64 ± 3.09 mL and 20.04 ± 1.82 mL, and residual volumes after 3 h were 3.36 ± 6.82 mL and 9.74 ± 1.50 mL. Except for the residual volume after 3 h, all these results were not statistically significant. Residual volume after 3 h was statistically significantly lower in the IBS patients than in the controls (P < 0.001). Ejection fraction of the gallbladder was significantly higher in the IBS patients than in the controls (84% vs 55%, P < 0.001).


Gallbladder contraction in patients with IBS was not different from that of a control group at post-prandial second hour but was signigicantly more pronounced at the end of 3 h when compared with controls. Ejection fraction of the gallbladder was higher in IBS patients when compared with controls.

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