Role of ambulatory blood pressure monitoring in patients with acromegaly

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Abstract

Background:

Hypertension is associated with increased cardiovascular deaths in patients with acromegaly.

Objective:

To evaluate the accuracy of blood pressure (BP) by 24-h ambulatory blood pressure monitoring (ABPM) and office BP measurements to represent the real BP status in acromegalic patients and its relationship with acromegalic activity and echocardiogram parameters.

Patients and methods:

Cohort of 37 patients with acromegaly in a tertiary endocrine outpatient service.

Results:

Twenty-three percent of the patients were considered hypertensive by ABPM versus 32% by office BP measurements (P = 0.006). BP obtained from the ABPM was associated with growth hormone, insulin-like growth factor type 1 levels and echocardiogram parameters of acromegalic myocardiopathy. Nondipper behavior presented a significant association with the hormonal profile.

Conclusion:

BP levels assessed by ABPM were associated with acromegalic activity and echocardiogram parameters. ABPM can correctly identify BP levels and their repercussion on acromegalic patients.

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