Large inter-arm differences in blood pressure are independently associated with cardiovascular disease and mortality. We investigated differences in inter-arm blood pressure for the general Korean population and identified factors associated therewith.Design and Method:
This cross-sectional study analyzed 806 participants aged 30 to 64 years without history of major cardiovascular disease who participated in the Cardiovascular and Metabolic Disease Etiology Research Center cohort study, which began in 2013. Brachial blood pressure was measured simultaneously for both arms using an automated oscillometric device equipped with two cuffs in the seated position. After five minutes of rest, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured three times; the averages thereof were analyzed. Multivariate logistic regression models were used to identify factors associated with inter-arm differences.Results:
The mean inter-arm difference was 3.3 mmHg for SBP and 2.0 mmHg for DBP. Large inter-arm differences (≥10 mmHg) in SBP and in DBP, respectively, were found in 3.7% and 0.9% of subjects. A large inter-arm difference in SBP was associated with mean SBP (p = 0.002) and C-reactive protein (p = 0.014), while that in DBP was associated with only body mass index (p = 0.015). Sex, age, and anti-hypertensive medication use were not associated with differences in inter-arm blood pressure.Conclusions:
Large inter-arm blood pressure differences are present in only a small portion of healthy Korean adults. Our findings suggest that high SBP, chronic inflammation, and obesity may be associated with larger differences in inter-arm blood pressure.