The role of ambulatory blood pressure (BP) monitoring ABPM) has not been well-studied in patients with resistant hypertension.Design and Method:
the retrospective study, 168 patients with resistant hypertension who had 24-hour ABPM and clinic BP measurements were identified. Resistant hypertension was defined as uncontrolled clinic BP while taking ≥ 3 medications including a diuretic or controlled BP while taking > 4 medications.Results:
Within the study group, ambulatory BP < 130/80 mmHg was found in 36.3% of all patients. Only 6.5% had both ambulatory BP < 130/80 mmHg and clinic BP < 140/90 mmHg, Prevalence of white-coat hypertension, masked hypertension, and sustained hypertension were 29.8%, 6.0%, and 57.7%, respectively. Compared with patients with sustained hypertension, more patients in the white-coat hypertension group had low nocturnal average systolic BP (defined as nocturnal average systolic BP < 90 mmHg, 14.0% vs 0%) and low 24-hour average diastolic BP (defined as 24-hour average diastolic BP < 60 mmHg) (46.0% vs 25.8%, P < 0.01).Conclusions:
ABPM provides more reliable assessment of BP in patients with resistant hypertension.