[PS 03-08] STRUCTURAL CHANGES OF THE BRAIN IN PATIENTS WITH ARTERIAL HYPERTENSION (AH) 2 DEGREE BY COMPUTED TOMOGRAPHY(CT)

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Abstract

Objective:

To evaluate the amount of atherosclerotic changes of the main cerebral vessels, the presence of atrophy and foci of ischemia in patients with arterial hypertension 2 degree.

Design and method:

All patients were divided into two groups according to the following criteria. Group 1 — AH 2 degree (70 patients). Group 2 — the lack of clinical and functional signs of hypertension (30 patients). The diagnosis of hypertension was established in accordance with the who classification and WOAH 1999 and 2004. The average age of patients in both groups was 58.6 ± 11, 01 years. In the main group were examined 45 men (64, 2%) and 25 women (35.7 percent). The average duration of hypertension was 9.75 ± 9, 15 years.

Results:

Identified CT signs of vascular encephalopathy, atherosclerosis of the main vessels of the brain, moderately expressed external hydrocephalus substitution type in the 1st group – in 41.4% of cases (29 patients out of 70); in the control group – in 10% of cases. Cystic-atrophic changes in the frontal lobe in 1 group - 10%; in 2 group – 7 %. Foci of CSF density subcortical centers in 1 group - 7.14% (5 of 70), 2 group - 0%. Agenesia of the corpus callosum 1 group - 8.5 %, 2 group - in 3, 33%. Cyst of posterior cranial fossa 1 group - 2.8 %, 2 group – 0%. The detected hardening of the occipital lobe in 1 group - 14.2 %; 2 group -13, 3 %.

Conclusions:

These data suggest that early brain examination of patients with hypertension 2 degree gives you the opportunity to identify a significant number of ischemic changes in the brain in hypertensive patients. The obtained data give the opportunity to allocate the risk of developing more severe complications hypertension of 2 degree and to plan their primary prevention.

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