A high transient ischemic dilatation ratio (TID) for the left ventricle (LV) from a gated myocardial perfusion imaging (G-MPI) is broadly believed to associated with Coronary Artery Diseases (CAD). Hypertension is one of risk factor for CAD. We investigated the relationship between coronary angiogram result with hypertension as predictor of CAD in patients with high TID ratio.Design and Method:
This was a retrospective study from all patients visiting nuclear medicine department for myocardial perfusion imaging (MPI) and cardiology department for coronary angiography at tertiary health centre Hasan Sadikin Hospital from January - December 2015. Patients who underwent MPI having a TID ratio ≥ 0.78 were included in this study. Quantitative perfusion gated parameters were obtained and means of summed stress scores (SSS), summed rest scores (SRS), summed difference scores (SDS), stress and rest ejection fraction (EF) were calculated. Visual interpretation was performed to classify the perfusion as normal, fixed, mixed (fixed and reversible defects), single reversible or multiple reversible defects. Coronary angiograms were assessed as normal with no CAD, single vessel, two-vessel or three-vessel disease. Correlation between coronary angiograms result in hypertensive and non-hypertensive patients with high TID ratio were studied using fisher's analysis with SPSS.Results:
A total of 66 patients with TID ratio ≥ 0.78, classified as hypertensive (mean TID 1,06 ± 0,13) and non-hypertensive (mean TID 1,01 ± 0,11). CAD on coronary angiograms was found in 91,8 % hypertensive patient (56 patients) showing significant correlation in Fisher analysis with P < 0,05 (p = 0,001) and OR 44,8 (95% CI 4,16 – 481,4).Conclusions:
Hypertension was a good predictor of significant CAD in patients with high TID score. Hypertensive patients with high TID ratio need coronary angiography for further workup for CAD.