PS 08-61 CLINICAL AND PARACLINICAL FEATURES IN GRADE 2 AND 3 HYPERTENSIVE WOMEN WITH ANGINA

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Abstract

Objective:

To evaluate some clinical, biological, echocardiographic and coronary angiographic findings in grade 2 or 3 hypertensive women accusing angina.

Design and Method:

From 342 women who were admitted in our department accusing angina and performed coronary angiogram between January and December 2014, there were included in study 51 subjects previously diagnosed and treated for grade 2 or 3 hypertension. Exclusion criteria: patients with grade 1 hypertension, history of acute myocardial infarction, angioplasty or severe valvulopathies.

Results:

Subjects were divided into two subgroups: first group: women with grade-2 hypertension, and the second group: women with grade-3 hypertension. There were no significant differences concerning comorbidities (diabetes, dyslipidemia, smoking) and biological exams (cholesterol, glycemia, triglycerides) in the two groups. 7 (35%) patients in first group vs. 4 (12.9%) in second group were pre-obese, 8 (40%) vs. 10 (32.26%) were obese class I, 0 vs. 9 (29.03%) were obese class II, and the rest had normal BMI (p = 0.024). 9 (45%) patients vs. 12 (38.71%) patients had class IV CCS angina (p = 0.48). The rest of the subjects were class I-III CCS or accused atypical angina. Echocardiogram revealed posterior wall thickness of 9.65 mm (+/−1.22) vs. 10.54 mm (+/−1.41) (p = 0.02) and left ventricular mass index (calculated only in 30 patients) was 161.6 g/m2(+/−42.99) vs.202.2 g/m2(+/−47.82) (p = 0.021). There were no differences in septum thickness or LVEF in the two groups. Regarding coronary angiography, 5 (25%) vs 7 (22.58%) patients had significant stenosis (p = 0.84).

Conclusions:

Obesity class II was found at clinical exam only in the group of grade-3 hypertensive women with angina. Furthermore, they seem to have signs of increased after-load and left ventricular remodeling more frequently. Whatsoever, we could not find other specific comorbidities or more significant coronary lesions in grade-3 compared with grade-2 hypertensive women with angina.

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