Evaluation of the prevalence of prehypertension (PHT) and its risk factors in a population becomes important to design preventive measures and hence reduce the burden of hypertension (HT). The study estimates association of PHT with metabolic risk factors in population-based sample of Russian Federation (RF) inhabitants.Design and Method:
A novel epidemiological survey of cardiovascular risk in regions of RF with different climatic, geographic, economic and demographic characteristics (ESSE-RF) was performed in a multi-step stratified random sample of approximately 1600 participants in 12 selected regions (Volgograd, Vologda, Voronezh, Vladivostok, Ivanovo, Kemerovo, Krasnoyarsk, Orenburg, Tomsk, Tyumen, Saint-Petersburg and Northern Osetia-Alania). Totally 20652 participants aged 25–65 years were examined. All subjects signed informed consent and filled validated questionnaires regarding lifestyle, concomitant disease and medication. Anthropometry, fasting blood sampling, blood pressure (BP) measurement were performed. Office BP was registered by OMRON (Japan) twice on right hand in sitting position with calculation of mean BP. Fasting serum lipids and glucose were detected by Abbot Architect c8000 (USA). Optimal BP was identified as BP<120/80 mmHg, PHT as BP = 120–139/80–89 mmHg, HT as BP ≥ 140/90 mmHg or antihypertensive treatment. Statistical analysis was performed using SPSS Statistics 20.Results:
Data analysis was possible in 20607 participants (7806 males (37.9%) and 12801 females (62.1%)), results are presented in table 1.Conclusions:
In Russian population prehypertension is associated with higher prevalence of metabolic disorders comparing with normotensive patients and twice lower than in hypertensive participants.