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The study was determined to study direct effect of various grades of isolated obesity on Echocardiographic indices of systolic and diastolic left ventricular function.

Design and Method:

Study consist of 3 groups. Group 1 (n = 23) consist of normal weight individuals with BMI (18.5–22.9kg/m2), Group 2 (n = 28) of overweight individuals with BMI (23–24.9kg/m2), Group 3 (n = 24) of obese individuals with (BMI > 25kg/m2). Echocardiographic indices of systolic and diastolic functions were obtained and dysfunction was assumed when at least two values differed by >2 SD from normal weight group. Ejection fraction was increased (p = 0.001) in group 2 and group 3. shortening was increased significantly in group 3 (<0.001). Left ventricular dimensions (EDD & ESD) were increased (p < 0.001, 0.002) but relative wall thickness was unchanged in group 2 & 3.


Systolic dysfunction was not observed in any of the obese patients. The deceleration time was increased (p < 0.01) in overweight and obese subjects compared to normal group individuals. No difference was found between obesity subgroups. Subclinical diastolic dysfunction in the form of reduced E/A ratio and increased deceleration time was more prevalent among obese subjects.


BMI correlated with significantly with indices of left ventricular diastolic dysfunction was noted in all grades of obesity which correlates with BMI.

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