Hypertension, obesity and diabetes (metabolic syndrome) are significant risk factors of stroke. A better understanding of relation between metabolic syndrome and hypertension may lead to the reduction of cerebrovascular risks and improve the stroke treatment and outcome as well.Design and Method:
A total of 345(F = 198, 69,7 ± 5,3) patients with acute stroke were investigated. Diagnosis of Metabolic syndrome (MetS) was ascertained according to the revised National Cholesterol Education Program Adult Treatment Panel III (ATP III-r). Stroke was diagnosed using NIHSS criteria. Type, side and site of stroke was assessed by MRI. Hypertension (HYP) was defined according to cardiovascular criteria, based on target organ damage. In addition to hypertension, other modifiable and non-modifiable risk factors were recorded. Neuropsychological battery and MMSE tests were performed.Results:
Among Stroke patients 124/35.9% found to have MetS, 106/85.4% diagnosed as ischemic stroke with lacunar or multiple brain lesions. Most of the patients with female preponderance (76) had moderate to severe leucoaraiosis (71%), mild-to moderate cognitive disturbances (54%) and dementia (14%). The HYP and obesity alone-146/42.3% patients had more haemorrhagic stroke (79/54.1%) with male dominance and psychological disturbances, such as depression (46%) or depression-anxiety disorders(31%).Conclusions:
Mets may be considered as independent risk factor for ischemia and dementia (P > 0.001), while the Hypertension and obesity alone may carry the risk of bleeding and neuropsychological disturbances (P > 0.001).