PS 16-15 THE ASSOCIATION BETWEEN SERUM URIC ACID AND HYPERTENSION IN SUDANESE PATIENTS.

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Abstract

Objective:

The aim of our study is to examine the association between serum uric acid and hypertension in Sudanese patients.

Design and method:

This is a cross sectional case control study held in Khartoum State, Sudan at 2015. Total number of the study group was 174, eighty four of them were known hypertensive, and 90 were sex matched controls. Fasting blood glucose was measured by calibrated glucometer. Parameters of lipid profile were determined by using clinical chemistry analyser (Echo, Italy) and commercial kits (Biosystem, Spain).

Results:

BMI, Fasting blood glucose, Cholesterol, Triacylglycerol, LDL-C and HDL-C were significantly higher among hypertensive patients versus controls. No significant difference was found in the mean uric acid between hypertensive patients and controls. Significant inverse correlation was observed between serum uric acid and fasting blood glucose [r = -0.306; P = 0.001]. Linear regression analysis showed positive significant correlation between serum uric acid level compared to age, male gender, BMI, triacylglycerol and cholesterol (P < 0.05).

Conclusions:

Unlike previous studies among other populations serum uric acid was not associated with hypertension among Sudanese patients. Interestingly a significant inverse correlation was found between fasting blood glucose and serum uric acid further studies are required to elucidate the impact of this correlation.

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