Genome-Wide Association Studies have found the majority of hypertension associated genetic variants, non-coding RNAs, which have not the ability of coding protein but influencing gene expression or affecting regions that control transcription. In this review, we focus on the relations of two classes of non-coding RNAs, micro-RNAs and long non-coding RNAs, and hypertension.Design and method:
The discovery provides an overview of mechanistic, clinical and diagnostic implications of miRNAs and lncRNAs in hypertension. Furthermore, we introduce the interaction between miRNAs and lncRNAs.Conclusions:
miRNAs and lncRNAs play an important role in hypertension.