PS 17-05 OUTCOME OF PATIENTS AFTER STENTING FOR RENAL ARTERY STENOSIS, SIGNIFICANT BLOOD PRESSURE AND RENAL FUNCTION REDUCTION

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Abstract

Objective:

To study post-renal artery stenting outcome of systolic and diastolic blood pressure (BP) and renal function at three (3) months, six (6) months, twelve (12) months and last follow-up.

Design and method:

Study population were patients with significant renal artery stenosis who underwent angioplasty with stenting in between January 1999 to September 2006. Baseline BP and serum creatinine levels were recorded and subsequently compare with respective results at three (3) months, six (6) months, twelve (12) months and at last follow-up. Generalized estimating equations were applied to analyze the changes in blood pressure and serum creatinine over time.

Results:

Total of thirty two patients, twenty one were Chinese, six Malay and five Indian were studied. The male to female ratio was 1.3:1. The mean age (± SD) was 69.4 ± 8.8 years. The mean follow-up time was 1.8 ± 1.6 years (range 0.5 to six years). Compared to the baseline BP, there was significant improvement at three (3) months, six (6) months, twelve (12) months and at last follow-up. In the diabetes mellitus (DM) arm, deterioration in serum creatinine was observed. In the non-DM arm, there was stabilization of serum creatinine with further improvement at twelve (12) months.

Conclusions:

Renal artery stenting can significantly improve BP and renal function in selected group of patients, especially patients without DM. As shown in this study, post-stenting, patients without DM have stable renal function or improvement while patient with DM, especially those with proteinuria, there is deterioration in renal function.

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