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Hypertension is a very common and important chronic disease, more than half of the patients having compliance problems in medication. Most of the people in Taiwan are covered by National Health Insurance. Population between rural and urban area are quite different. It is important to understand the difference of compliance in hypertensive patients between these two area.According to previous studies, the factors influence the compliance include: (1) socioeconomic status (2) patient's knowledge of their disease and health behavior (3) patient's knowledge of their therapy and medication (4) social and family support (5) patient-doctor relationship and (6) self-perceived convenience. A questionnaire based upon 6 items and patient general data was designed. Patients were chosen at random in outpatient clinics to fill the questionnaire under a guide of a trained investigator.There were 173 patients with 43 having poor compliance in group practice centers(GPC) and 165 patients with 33 having poor compliance in local hospitals(LH) enrolled for the study. A comparison between patients with good and poor compliance was made. No significant difference in the influence factors among the GPC but there was significant difference in the factor 3,5, and 6 among the LH group. For the patients with good compliance, the comparison between LH and GPC showed a better performance in the factors 2 and 5 among GPC patients, but the factors 1 and 4 were better among LH patients. For the patients with poor compliance, a worse performance in the factors 1, 4 and 6 among GPC was found, but the factors 2 and 5 were worse among LH patients.There were different influence factors of compliance in hypertensive patients in different medical facilities. Using this mode of comparative study, the factors performed better or worse can be more clearly delineated and be helpful to improve patient compliance.