PS 17-83 COGNITIVE FUNCTION IN PATIENTS WITH DIFFERENT FORMS OF ATRIAL FIBRILLATION

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Abstract

Objective:

Atrial fibrillation (AF) causes a impairment in cognitive function (CF) due to fluctuations in cardiac output and the decline of cerebral blood flow.

Design and method:

To identify differences of cognitive impairment (CI) in different forms of AF, we included 100 patients with AF (56 men and 44 women) aged 62,7 ± 1,3 years. Patients divided into 2 groups: 50 people with permanent AF (group 1) and 50 people with paroxysmal AF (group 2). All patients were examined physically and instrumental (ECG, echocardiography, daily monitoring). Program «Status PF» (Russia) was used to assess the CF (visual memory, attention, vision field, cognitive abilities, Neurodynamics.

Results:

In the first group of patients reproduced 3,8 ± 0,2 two-digit numbers and 4,5 ± 0,2 words, and in 2 group of patients 3,7 ± 0,2 two-digit numbers and 4,7 ± 0, 2 words. Assess of attention was made in two tests: put in order the numbers and the location of the figures. Patients with permanent AF put in order the numbers within 35,9 ± 2,3 seconds and marked the location of 4,4 ± 0,3 figures. Patients with paroxysmal AF put in order the numbers within 30,0 ± 1,5 sec and marked the location of 5,1 ± 0,3 figures. The first group scored 14,7 ± 1,2, 7,8 ± 0,4, 4,0 ± 0,4 points in tests on an analogy, induction and abstraction intellection. In second group these figures were 16,3 ± 1,3, 8,4 ± 0,3, 4,1 ± 0,4 points. Options Neurodynamics (simple and complex hand-eye reaction) in the first and second group were 678,6 ± 23,6 and 629,2 ± 27,3 msec.

Conclusions:

CI has no significant difference in patients with permanent or paroxysmal form AF. And in paroxysmal AF this is frequent cerebral microembolism in restoring sinus rhythm.

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