PS 18-06 EFFECTS OF NOISE AND LEAD ON BLOOD PRESSURE

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Abstract

Objective:

The effect of noise and lead on blood pressure (BP) has not been fully understanded. The purpose of this study was to know the effects of noise and lead on BP.

Design and Method:

284,616 workers classified into four groups according to their exposure of the lead and noise at worksite: non exposure, lead exposure, noise exposure, co-exposure(coE). The multivariate logistic regression analysis used. The following variables were calculated as covariates: age (5-year intervals), other metal exposure body mass index and total cholesterol.

Results:

The odds ratio (OR)s of hypertension (HTN) are statistically significant higher in lead exposure (OR 1.19, 95% CI, 1.12 - 1.26) and noise exposure (OR 1.35, 95% CI, 1.32 - 1.39) than non-exposure. The OR of HTN is statistically significant lower in coE (OR 0.79, 95% CI, 0.73 - 0.86) than non-exposure. The OR of high systolic BP (140 mmhg) is statistically significant higher in noise exposure (OR 1.36, 95% CI, 1.33 - 1.39) than non-exposure. The OR of high systolic BP (140 mmhg) is statistically significant lower in coE (OR 0.75, 95% CI, 0.68 - 0.82) than non-exposure. The ORs of high diastolic BP (90mmhg) are statistically significant higher in lead exposure (OR 1.19, 95% CI, 1.12 - 1.27) and noise exposure (OR 1.35, 95% CI, 1.32 - 1.38) than non-exposure. The OR of high diastolic BP is statistically significant lower in coE (OR 0.80, 95% CI, 0.74 - 0.87).

Conclusions:

The noise exposure increased systolic and diastolic BP and the lead exposure increase diastolic BP. The coE lower BP and the proportions of HTN.

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