To assess the association between blood pressure (BP) and body fat distribution in children.Design and Method:
In a multi-center study, 10,471 children aged 6–18 years were recruited from seven Chinese cities. Fat distribution was determined via whole body scans by dual-energy X-ray absorptiometry (DXA) (Hologic Discovery A, USA). Blood pressure was measured in the sitting position on the right hand using the electronic sphygmomanometers (OMRON HEM-7012) for three times at proper room temperature. High blood pressure was defined by the blood pressure reference standards for Chinese children and adolescents. Anthropometry and blood sample was conducted by the technicians who were strictly trained. Regression analysis was used to explore the relationship between BP and fat distribution.Results:
The children of high blood pressure had a higher body mass index (BMI) (21.39 vs. 19.20 kg/m2), waist circumference (71.41 vs. 65.55 cm), trunk fat (7.13 vs. 5.33 kg) compared with children of normotension. Trunk fat had a significantly positive relationship with systolic blood pressure (β:1.69, 95%CI: 1.41–1.97, P < 0.001) and diastolic blood pressure (β:0.92, 95%CI: 0.70–1.14, P < 0.001) adjusted for sex, age, height and total fat.Conclusions:
Greater trunk fat was associated with higher blood pressure in Chinese children.