[PP.03.14] CLINICAL AND PARACLINICAL IMPACT IN PATIENTS WITH LONGSTANDING SYSTEMIC HYPERTENSION

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Abstract

Objective:

to assess the clinical and paraclinical impact in patients with longstanding systemic hypertension (SH) in adherent controlled subjects.

Design and method:

180 patients with SH examined in the last 3 years were included. It was a retrospective study. In all patients were recorded retrospective data regarding medical familial history, clinical findings, stress exposure, blood tests, ECG (the last one), echocardiography (the last one) and depending on clinical status and comorbidities ECG Holter, blood pressure Holter, pro-BNP determination or other paraclinical tests. Al the subjects were hypertensive for at least 12 years (18.7 years average). In the study group the medium value of BP was 138 /88 mmHg (between 70–155 mmHg.

Results:

Baseline characteristics: study group (n = 180) – age - 57.3 y; 52% males; 35% smokers, 64% dyslipidemia; associated T2DM 27%, obesity 52%, ischemic heart disease 32%, hyperthyroidia 9%, other 19%; in treatment with ACEi, AT1RA, beta orcalcium channel blockers, diuretics, alpha metil dopa, statins.

Results:

control group – without SH or other cardiovascular morbidities - (n = 120) – average age - 51.2; 49% males; 23% smokers, 47% dyslipidemia; associated T2DM 12%, obesity 40%, hyperthyroidia 4%, other 17%; in treatment with statins.

Results:

The echo findings were: - in the study group: LA – 49.3 mm, LVEDD-60.2 mm, EF 49.7%; in the control group LA – 37.4 mm, LVEDD-43.5 mm, EF 69.2.

Results:

In study group: ECG – heart rate 78 beats/min; 12 RBB, 4 LBB, 12 AV block I degree, repolarization changes in 87 patients, 16 AF; NYHA II class – 56 pts.

Results:

In the control group: ECG - heart rate 69 beats/min; 3 RBB, 1 LBB, 7 AV block I degree, repolarization changes in 18 patients, 1 AF; no heart failure.

Conclusions:

The longstanding essential SH has a mild to medium impact in controlled adherent pts. even after more than 25 years of evolution if considering the subjects without important comorbidities. Though in the study group the echo and ECG findings are more significant. The remodeling process is less important, the ECG findings, capacity of effort quality of life are not far from the control group.

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