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Mounting evidence suggests that essential hypertension (EH) has a negative impact on health-related quality of life (HrQoL). Diabetes mellitus type II (DM-II) is associated with marked acceleration of vascular aging. We assessed the hypothesis that the combination of EH with DM-II could have an additive detrimental effect on H-rQoL.

Design and method:

We examined 145 subjects with newly diagnosed, untreated uncomplicated stage I-II EH (aged = 56 ± 16 years, DM-II = 37, office blood pressure = 156/92 mmHg). The validated Greek version of the Short Form 36 (SF-36) General Health Survey questionnaire was administered to all participants. The SF-36 is a generic H-rQoL instrument that includes eight subscales: physical functioning, physical role, bodily pain, general health, vitality, social functioning, emotional role and mental health. The subscales were further grouped into two summary scales: the physical component summary (PCS) and the mental component summary (MCS).


Diabetic hypertensives demonstrated lower scores in all SF-36 dimensions compared to non-diabetics (Table).


Hypertension accompanied with DM- II exerts a deleterious effect on health-related quality of life. Perhaps the earlier identification of hypertensive subjects with DM-II, may improve not only the cardiovascular outcome but also the cability to cope with everyday needs.

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