[PP.11.19] BLOOD PRESSURE CONTROL AND VASCULAR RISK TREATMENT IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE OF LOWER EXTREMITY

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Abstract

Objective:

Peripheral arterial disease (PAD) of lower extremity is predominantly a manifestation of atherothrombotic process in which arterial hypertension plays an important role in initation as well as progression of the disease The aim of the present study was to determine risk factor profile, blood pressure control in PAD patients and describe global cardiovascular risk treatment.

Design and method:

Observational and descriptive study was carried out in 120 hospitalized patients not for vascular disease primary (59 M/61 F, 73 ± 12 years of age). PAD was determined by an ankle brachial index (ABI) < 0,9 and blood pressure control by 24-hour blood pressure monitoring in all patients. Patients with critical limb ischaemia were excluded.

Results:

Profile of symptomatic and asymptomatic (55%) PAD patients with ABI < 0.9 was: high blood pressure 89.2%, diabetes mellitus 83.3%, lipid disorders 72.5%, smoking 35.8%, creatinine clearence < 60 ml/min 38.3% and all components of metabolic syndrome (IDF) in 36.6% of patients. Mean 24-hour blood pressure was 141/78 ± 14/8 mmHg, pulse pressure 63 ± 9 mmHg, 65.8% of non-dippers. Lipid -lowering agents were present in 53%, ACE- inhibitors in 44% and antiplatelet therapy in 74% patients.

Conclusions:

There is a high prevalence of asymptomatic PAD patients that can be detected by an ABI. In PAD patients is commonly systolic hypertension associated with a high pulse pressure and non-dipping pattern. Efective blood pressure control and global cardiovascular risk treatment are underestimated in clinical practice despite significantly increased cardio-cerbro-vascular mortality and morbidity in symptomatic and even in asymptomatic PAD patients.

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