Our aim was to study any possible correlation between indices of diastolic/ systolic function of the left ventricle to the 24-hour blood pressure (BP) variability among hypertensive patients.Design and method:
845 hypertensive patients (438 males), treated (N = 222) or newly diagnosed untreated (N = 623), mean age of 52 years, body mass index: 27 kg/m2, mean systolicBP/ diastolicBP: 143/91 mmHg and mean heart rate of 76 beats per minute, underwent 24-hour ambulatory BP recording and transthoracic echocardiographic/Doppler exam. The early-diastolic and end-diastolic velocities of the transmitral valve flow were recorded.Design and method:
In a subgroup of 105 patients, indices of diastolic and systolic function of the left ventricle were measured using Tissue Doppler Imaging (TDI). The aforementioned parameters were correlated on the 24-hour BP variability and possible correlations between them was examined for values of 24-hour SBP variability >15 mmHg or <15 mmHg.Conclusions:
In hypertensive patients, treated or newly diagnosed untreated, the 24-hour variability of the SBP significantly correlates principally with indices of left ventricle's diastolic function and its filling pressures, as well as with indices of its systolic function.