[PP.17.19] ORTHOSTATIC HYPOTENSION REACTIONS IN HYPERTENSIVE PATIENTS

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Abstract

Objective:

The aim of our study was to investigate the relationship between the orthostatic hypotensive reactions (OHR) identified active and passive OT in patients with AH older age groups

Objective:

(22 M, 49 F) with AH grade I-III, av.age 68,1 ± 5,8 years. During OT BP (beat to beat) measured continuously and non-invasively using the “Task Force Monitor “(“CNSystems” Austria). The criteria for IOH was considered the onset of symptoms of cerebral hypoperfusion associated with a reduction in SBP > 40 mmHg and DBP > 20 mmHg in the first 5–15 seconds orthostasis (Wieling W., 2006) and the identification of the initial uncompleted depressor reactions of BP (Rogoza A et al., 2008). Control of cognitive function was performed by a research brief mental status (MMSE), clock drawing test and concentration test by the method of TM. The statistical analysis was carried with Statistica 6.0.

Results:

In 22 (31%) patients was found the OHR. The groups were comparable by age (68,5 ± 5,5 vs 66,8 ± 5,9) yrs, gender (F 13 (59%) vs 37 (76%)); duration of AH (18,7 ± 11,7 vs 15,3 ± 10,6) years. The pts in the gr. with OHR had a more frequent strokes n = 3 (14%), without OHR – TIA in 4 pts (8%). Significant differences have been found between the groups by atherosclerotic lesions (40 < plaque < 65) of the carotid arteries (in gr. OHR 10 (45%) vs 3 (6%) without OHR, p < 0,05). The study revealed significant cognitive differences in patients with OHR and without OHR. Results of the test clock drawing OHR patients were lower than in patients without the PER (7,2 ± 1.4 vs 8,3 ± 0,8, p < 0,04), during the TM in patients with PER showed a reduction in attention (21,2 ± 2,4 vs 22,5 ± 1,17. p < 0,02). During the MMSE test revealed no significant differences (25,6 ± 2,45 vs 26,8 ± 1,3.p > 0.05).

Conclusions:

Hypertensive patients in older age groups with various types of OHR (the initial and classic) have a reduction of memory and attention, atherosclerosis of the carotid arteries, strokes in anamnesis compared with the same category of patients without the OHR.

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