[PP.17.22] SYNDROME COGNITIVE IMPAIRMENT AND QUALITY OF LIFE IN PATIENTS WITH HYPERTENSION

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Abstract

Objective:

Clinical studies in recent years indicate that there is a significant statistical association between the levels of systolic and diastolic blood pressure (BP) and indicators of cognitive function (CF) in patients with arterial hypertension (AH) is not dependent on the level of education, smoking history, comorbid disease. To study the structure of cognitive disorders (CD) and quality of life (QOL) in patients of working age with AH 1-2 stages and the relationship to the overall risk of cardiovascular events.

Design and method:

Observed 90 patients with AH 1-2 stages of the standard cardiology protocols, additional diagnostic procedures include: neuropsychological evaluation (integrated assessment CF scale MMSE, FAB, the study of memory technique Remembering 10 words and the method of Luria, attention and speed of sensorimotor reactions - by Schulte and Rybakov) analysis of quality of life - on the SF-36 questionnaire, the overall risk of cardiovascular events - on a scale SCORE. The average age of the patients was 55,7 ± 7,9 years, mean duration of AH - 11,8 ± 5,7 years.

Results:

AH patients of working age, are included in the study were light (35.4%), moderate (56.1%) CD and 8.5% - has mild dementia. For the most part suffered the processes of concentration, psychomotor speed and verbal memory, which affects the quality of life indicators: women were more pronounced decrease in vitality and social functioning (46,87 ± 2,60 and 52,50 ± 4,08, respectively), and men - mental health and emotional role functioning (42,37 ± 3,50 and 47,33 ± 6,45, respectively). However, the analysis of total cardiovascular risk is found that 25% of them are likely to develop fatal cardiovascular events was less than 1%, 17% - the probability was 2%, 14% - 3-4%, 10% - 5-9% 6% - 10–14%, and only 3% of the patients - 10-year risk of cardiovascular events was 15%.

Conclusions:

Patients of working age with AH 1-2 stages and low risk of fatal cardiovascular events formed CD, defining the low quality of life that determines the need for early detection and correction of the CF to improve the prognosis of the disease.

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