[PP.23.17] PREDICTORS OF LONG TERM SUCCESS IN RENAL DENERVATION

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Abstract

Objective:

We studied the importance of the duration of treatment and norepinephrine levels with respect to long term success of renal denervation.

Design and method:

In this prospective cohort study with 54 patients suffering from resistent hypertension, 22 women and 32 men, 62 years old SEM ± 1.4, first diagnosed 13.8 years ago SEM ± 1.7, receiving 5.3 SEM ± 0.2 hypertension lowering agents, norepinephrine levels were measured at standardardised conditions before intervention and after 6 and 12 months.

Design and method:

Two devices were used:

Design and method:

Medtronic SimplicityTM (n = 45) and St. Jude Medical EnligHTNTM (n = 9) Patients hypertension was treated about 14 years with different combinations of medical therapy.

Design and method:

Data analysis were performed with Graphpad Prism Software using the Student's t-test. A p-value < 0.05 indicates a statistically significant difference.

Results:

Please see images in the previous page.

Conclusions:

Norepinephrine levels, but not the duration of hypertension, could be a predictor for long time success in renal denervation.

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