[PP.23.18] ASSOCIATED FACTORS OF NOT ACHIEVING BLOOD PRESSURE GOALS IN TUNISIAN RESISTANT HYPERTENSION POPULATION: REAL WORLD PRACTICE

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Abstract

Objective:

Achieving blood pressure (BP) goals in resistant hypertension (RH) is important to prevent clinical complications such as stroke, aortic dissection, myocardial infarction, congestive heart failure, and renal failure.

Objective:

Scanty information is available on resistant hypertension in our country. This study allows us to assess the main risk factors of not achieving BP goals in a Tunisian RH population.

Design and method:

The study was carried out in 109 adults with RH living in the region of the southeast of Tunisia. According to BP goals achievement after 6 months, patients were divided into two groups: with (n = 68) and without BP goals achieving (n = 41). We aimed to determine the factors of non achieving BP goals.

Results:

Mean age of the patients was 70.3 ± 10.7 years and 62.4% were female. More than half of the subjects (53.2%) had diabetes mellitus, obese (33%), and (35.8%) with renal function impairment.

Results:

Clinical BP values amounted to 146.4 ± 27.3/81.7 ± 13.6 mmHg despite the daily use of 3.7 ± 0.7 drugs and a medication adherence rate of 87.3%. BP goals were reached in 62.4% of the patients.

Results:

In multivariate logistic regression analysis, not achieving BP goals in RH patients is more likely to be associated with cigarette smoking odds ratio (OR) 3.9, 95% confidence interval CI [0.94–16.09], obesity (OR) 2.65, 95% CI [1.04–6.78] and medication no-adherence (OR) 15.05, 95% CI [3.01–75.07].

Conclusions:

In our RH patients, to achieve BP goals we should promote compliance to hypertension medications and reducing both cigarette smoking and obesity.

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