[PP.24.16] CORRELATION BETWEEN PULSE WAVE VELOCITY AND HEART RATE VARIABILITY IN PREGNANT WOMEN WITH PREECLAMPSIA

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Abstract

Objective:

To investigate the correlation between pulse wave velocity (PWV) and heart rate variability (HRV) in pregnant women with preeclampsia (PE). Pulse wave velocity (PWV) is the most popular index to assessment the arterial stiffness

Design and method:

The analysis was performed in 155 women, mean age- 26–42 years with PE and 10 with normal blood pressure volunteers. The PWV were exanimate a non-invasive digital volume pulse (DVP) measuring system using a dual channel simultaneous measurement method. The changes of systolic and diastolic blood pressure and of pulse rate after active standing were registered noninvasive.

Design and method:

The RR intervals were recorded by means of MP 100 computerizes system with ECG module and the maximal –minimal interval during deep breathing (HRdb), the Valsalva ration (VR), and the 30:15 ratio were calculated automatically.

Results:

The PWV of CH group is significantly higher than those of normal blood pressure. (P < 0.05), the reflexion index (RI) and arterial stiffness index (SI) parameters in PE group are markedly higher than those in controls. RR variability is positively related with PWV in two groups, but the correlation in PE group is better than those in controls. Our results reveal abnormal cardiovascular responses with significant decrease of the HRdb response, the VR and the 30:15 ratios in the patients in comparison to the controls. The abnormalities were asymptomatic in 59% of the patients.

Conclusions:

PWV should be as another important clinic index to evaludte PE risk and the effect of PE treatment during pregnancy.

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