[PP.32.13] AN AGE-RELATED COMPARISON BETWEEN COMORBIDITIES AND TREATMENT OF HYPERTENSIVE PATIENTS

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Abstract

Objective:

Hypertensive patients with multiple chronic conditions are a priority population for health research. The objective of the study was to comparatively analyse age specific comorbidities and treatment of hypertensive patients.

Design and method:

The study included 200 patients with arterial hypertension consecutively hospitalized in the Internal Medicine Clinic of a University Emergency Hospital, in 2015. We compared 2 groups of hypertensive patients: younger than 75 years (group 1) and older than 75 years (group 2). We analyzed data from the hospital record database, using Analyse-IT software.

Results:

The distribution by sex in the group of study: 122 men (61.60%) and 78 women (38.40%). The distribution by age: 154 patients in group 1, 46 patients in group 2. The majority of hypertensive patients over 75 years were men (p = 0.0002). There were no significant differences in the severity of hypertension, grade of left ventricle hypertrophy and left ventricular ejection fraction, frequency of diabetes or chronic kidney disease, between the 2 groups. We have found a significant higher frequency of dyslipidemia in group 1 (p = 0.01). Instead, patients over 75 years old had a higher frequency of heart failure (p = 0.0001). 33% of patients from group 2 had coronary heart disease, as compared with 16% from group 1 (p = 0.04). 35% of patients from group 1 were obese, as compared with 9% of patients from group 2 (p = 0.0008). Regarding the treatment, we did not find any significant difference in the proportion of patients treated with ARBs, calcium channel blockers, diuretics, central antihypertensives, between the 2 groups. Instead, ACE inhibitors were prescribed more frequent in group 1 (70%) versus group 2 (53%).

Conclusions:

In our study, elderly hypertensive patients over 75 years old had a higher frequency of coronary heart disease and heart failure. Instead, they had a lower frequency of dyslipidemia and obesity. The antihypertensive treatment was similar in both groups, but less patients over 75 years old received ACE inhibitors. Evaluating the frequency of different comorbidities in hypertensive patients could help in planning appropriate strategies. Medical needs might be specifically addressed.

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