Diabetes mellitus (DM) and lipid disorders in hypertensive patients are associated with higher risk of cardiovascular complications and poor outcome and require more aggressive treatment strategies and follow-up. The main objective of this study was to describe trends in prevalence of DM and lipids disorders in adult hypertensive patients referred to specialized cardiology clinic during the period of January 2010 - December 2014.Design and method:
Data included 59268 (21153 males and 38115 females) patients, mean age 58.3 ± 13,8 years, referred to specialized clinic due to uncontrolled hypertension. Descriptive statistics were used to estimate the means in gender and age [under 35 years (n = 4079), 35–49 (n = 8566), 50–65 (n = 26381), older than 65 (n = 20242) years] subgroups. Linear regression was employed to determine the yearly trends. Age and gender-specific results were adjusted to Saint-Petersburg general population data for 5-years period and every studied year.Results:
The average prevalence of known lipid disorders for the studied period was 3,7% (2160 patients) without any significant 5-years trends. Increased level of total cholesterol in combination with increased low density lipoprotein levels was the most frequent disorder (917 cases; 42,7%). There were no significant changes in prevalence and characteristics of lipids disorders in gender subgroups. Analysis of age groups demonstrated increase in lipid disorders frequency in patients over 65 years (R2 = 0,80; p = 0,04). The average prevalence of known diabetes was 14,5% (8592 patients) and impaired glucose tolerance 0,9% (518 cases) without any significant trends during studied period in overall population and in gender subgroups. While in subgroup of hypertensive patients over 65 years there was an increase in prevalence of diabetes and impaired glucose tolerance during the last 5 years (R2 = 0,78, p = 0,05 and R2 = 0,95 p = 0,005, respectively).Conclusions:
During the last 5 years age older than 65 was associated with increase in prevalence of metabolic disorders in difficult to control hypertension. These trends can be important for the total risk reduction in the elderly and explain poor blood pressure control in this subgroup.