[PP.33.09] THE RELATIONSHIP BETWEEN RIGHT AND LEFT VENTRICLES IN PATIENTS WITH HYPERTENSION AND HEALTHY CONTROLS

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Abstract

Objective:

The aim of the study was to estimate the diastolic ratio between right and left ventriclein groups of hypertensive patients and healthy controls.

Design and method:

We examined 40 healthy controls and 103 hypertensive patients (41 treatment naive and 31 with well controlled HT and 31 resistant controlled HT). Measurements of the RV and LV diastolic function as well as LV structure were assessed by echocardiography (Toshiba Xario XG) using Tissue Doppler analyzer. The ANOVA test was used to compare differences between groups and the Statistica Pearson test was used to compare the correlation between parameters LV to RV.

Results:

SBP–systolic blood pressure, DBP–diastolic blood pressure,DcTt – deceleration times, E/A–ratio of the ealry (E) to late (A) ventricular filling velocities of mitral (m) or tricuspid (t), E’–early diastolic of mitral (m) or tricuspid (t) annular velocity, E/E’m–ratio of the early ventricular filling velocity to early diastolic of mitral (m) or tricuspid (t) annular velocity, EF -ejection fraction.

Conclusions:

In all groups of hypertensive patients LV massand diastolic dysfunction increased in comparison to healthy controls in post-hoc tests. We found statistically significant correlation between diastolic dysfunction of right and left chamber including the following parameters E/Am, E/E’m, E’m,E/At, E/E’t, E’t,except the deceleration time (DcT).

Conclusions:

These results suggest that hypertension causes parallel and gradual increase of diastolic dysfunction in both heart chambers.

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