Evaluation contribution of excess body weight (BW) in increase of aortic rigidity in young adults.Design and method:
171 students (105 boys and 66 girls) were screened for profile risk factors (RF) on results of survey, anthropometry, strip diagnosis (lipids and glucose). Study included people without disorders of glycemic and lipid status. Parameters of CP were determined using diagnostic complex BPLab Vasotens (Peter Telegin, Russia). Evaluated such marks as systolic BP aortic, diastolic BP aortic, index of augmentation in aorta (AIxao), pulse pressure amplification and others. To determine the contribution of overweight in increasing of aortic stiffness we used conjugation tables and assessed odds ratios and confidence intervals. To eliminate the influence of BP on the vessel rigidity all people were divided into 2grupps: 1gr. – hypertension / prehypertension (AH/PH) and 2gr. - normal/optimal BP. In presence of other RF both groups were quite comparable.Results:
It found in boys of 1st group with signs AH/PH if they have overweight chance of detection of increased AIxao is 3.6 times higher than among their peers with normal BW. In young men from 2nd group with normal/optimal BP probability of detection of cases increased aortic stiffness was 2.7 times higher than among students with normal BW. Among girls with signs of AH/PH if they have overweight high probability of detecting enlarged IAao increased by 21% compared to comparison group. For girls with normal/optimal BP risk to indicate of increased AIxao among those with overweight does not differ from girls with a normal BW.Conclusions:
Sex and belonging to different ranges of BP affect on the value of contribution of overweight in the increasing of AIxao. A more significant contribution of inlarged index BW in improving aortic rigidity is recorded among boys compared with girls. Moreover, the presence of AH/PH in boys increase this contribution to 1.5 times compared to normotensive state. Among girls effect of overweight on the studied parameters was much weaker. This data is advisable to take into account formation of groups of CV risk among youthers for realization of personalized prevention programs among them.