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We investigated the prevalence of cardio-cerebrovascular risk factors in the middle-aged and elderly community population to determine the 10-year risk for coronary heart disease for the further risk management.1140 subjects aged 40 years or older was selected from May 2016 to July 2016 in two communities in Fujian Province. The demographic information, physical examination and laboratory examination were conducted. Binary logistic regression or covariance analysis was used to analyze the relationship between cardio-cerebrovascular risk factors and education levels or average income levels.1. The subjects including 382 men and 758 women, with the average age of 57.9 ± 10.1 years. 198 subjects with high risk of stroke were screened out (17.4%). The 10-year risk for coronary heart disease was 2% (1%, 8%). 2. Prevalence of hypertension and diabetes, which standardized by age in the population, were significant lower while prevalence of dyslipidemia and atrial fibrillation were higher in men than those in women (all P < 0.05). 3. There were higher proportion of high risk of stroke among men, urban residents, population with higher education levels, higher income levels and older population (all P < 0.05). 4. The 10-year risk of coronary heart disease was higher in urban residents, the population with higher education levels, higher income levels, higher risk of stroke, heavy drinking and diabetes (all P < 0.05).The prevalence of cardio-cerebrovascular risk factors and proportion of high risk of stroke were higher in the middle aged and elderly population. Framingham risk score and stroke risk rating can be complementary for the prediction of cardiovascular and cerebrovascular diseases.