A13569 Relationship Between Ambulatory Blood Pressure Characteristics and Prognosis in Patients with Acute Hemorrhage Stroke

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Objectives:To investigate the change of ambulatory blood pressure (BP) for 7 days after admission and its impact on the prognosis for patients with acute hemorrhage stroke (AHS).Methods:141 patients with new onset AHS were enrolled. The 7-day/24-hour (24 h) ambulatory BP and clinical data was collected. The prognosis of patients was determined according to the 30-day Glasgow outcome scale (GOS) after admission, and the relationships of prognosis and ambulatory BP changes such as admission systolic BP (SBP) and diastolic BP (DBP), 7-day daytime/nighttime mean SBP and DBP, etc., were analyzed.Results:7-day /24-h mean BP decreased gradually among patients with new onset AHS. The BP on the seventh day was significantly lower than that on the first day (P < 0.05). There was no significant difference in BPCR between two groups (P > 0.05). There were significant difference between two groups in 7-day/24-h BP, admission Glasgow coma scale (GCS), white blood cells (WBC), hospital days, midline shift, broken into the ventricle, history of hypertension, and admission SBP (P < 0.05). Multivariate logistic regression showed that admission high 24-h mean SBP, low admission GCS, high WBC, big amount of bleeding, basal ganglia hemorrhage were the risk factors for the poor prognosis of AHS (P < 0.05).Conclusion:7-day/24-h BP was higher in the poor prognosis group among patients with new onset AHS, and admission severe disease, big basal ganglia hemorrhage, high admission 24-h SBP were indicators for the severity of condition and poor prognosis. Monitoring and control of admission 24-h SBP and the amount of bleeding are beneficial for improving the prognosis of AHS.

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