Biotinylation of aminopyridine-based macrocycles and metallomacrocycles and inclusion of biotinylated iron(II) complex in avidin

    loading  Checking for direct PDF access through Ovid

Abstract

A simple methodology for single-site conjugation of macrocycles and metallomacrocycles with biotin is presented. This method has been used to conjugate a redox-active macrocyclic complex and embed it into avidin. The resulting biotin-metal complex-avidin adduct exhibits peroxidase activity as shown by the oxidation of ABTS and pyrogallol with H2O2.

Related Topics

    loading  Loading Related Articles