Regional right ventricular function and timing of contraction in healthy volunteers evaluated by strain-encoded MRI

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Abstract

Purpose:

To prospectively determine the feasibility and accuracy of strain-encoded (SENC) magnetic resonance imaging (MRI) for the characterization of the right ventricular free wall (RVFW) strain and timing of contraction at 3.0 Tesla (3T) MRI.

Materials and Methods:

In 12 healthy volunteers the RVFW was divided into three segments (anterior, lateral, and inferior) in each of three short-axis (SA) slices (apical, mid, and basal) and into three segments (apical, mid, and basal) in a four-chamber view. The study was repeated on a different day and interobserver and interstudy agreements were evaluated.

Results:

Maximal systolic longitudinal strain values were highest at the apex and base, with a pronounced decrease in the medial segments (apex: –19.1% ± 1.4; mid: –17.4% ± 2; base: –19.4% ± 2.4, P < 0.001), and maximal systolic circumferential strain showed the highest values at the apex (apex: –18.1% ± 1.7; mid: –17.6% ± 1.2; base: –16.6% ± 0.9, P < 0.001). Peak systolic longitudinal and circumferential shortening occurred earliest at the apex compared to the mid-ventricle and base. Excellent interobserver and interstudy correlation and agreement were observed.

Conclusion:

The use of SENC MRI for the assessment of normal RV contraction pattern is feasible and accurate in 3T MRI. J. Magn. Reson. Imaging 2008;28:1379–1385. © 2008 Wiley-Liss, Inc.

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