Physical Activity Correlates With Neurological Impairment and Disability in Multiple Sclerosis

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This study examined the correlation of physical activity with neurological impairment and disability in persons with multiple sclerosis (MS). Eighty individuals with MS wore an accelerometer for 7 days and completed the Symptom Inventory (SI), Performance Scales (PS), and Expanded Disability Status Scale. There were large negative correlations between the accelerometer and SI (r = −0.56; ρ = −0.58) and Expanded Disability Status Scale (r = −0.60; ρ = −0.69) and a moderate negative correlation between the accelerometer and PS (r = −0.39; ρ = −0.48) indicating that physical activity was associated with reduced neurological impairment and disability. Such findings provide a preliminary basis for using an accelerometer and the SI and PS as outcome measures in large-scale prospective and experimental examinations of the effect of physical activity behavior on disability and dependence in MS.

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