Memory guided saccade deficit after caudate nucleus lesion

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The role of the caudate nucleus in ocular motor control is not well determined in humans.Eye movements were recorded from a 45 year old man with infarctions involving bilaterally the body of the caudate nucleus, with a greater extent on the left side. The patient exhibited a pattern of eye movement abnormalities in which a delay dependent decrease of accuracy of memory guided saccades predominated. By contrast, memory guided pointing was normal. It is concluded that the body of the caudate nucleus participates in a spatial short term memory network devoted to eye movements.

(J Neurol Neurosurg Psychiatry 1999;66:524-527)

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