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Biosample collection is essential to developing therapeutics for Huntington’s disease. Biosample collections are intended to accelerate progress towards the development of therapeutics that will benefit HD-affected individuals.Towards that goal, the longitudinal, code-protected clinical data and renewable and non-renewable biosamples collected from Enroll-HD, Registry-HD, Track-HD, Track-ON, HDClarity participants are made available to any interested researcher working at a recognized research institution through a straightforward qualification process. The wide availability of these resources aims to energize HD research and encourage a broad variety of ideas and projects. Provided that participants have consented to biobanking, their biological samples collected at baseline and each follow-up visit are used to derive non-renewable and renewable materials made available in aliquots.