Contrast-enhanced sonography in the diagnosis of hepatic hemangiomas: Atypical appearance due to the washout of microbubbles

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Contrast-enhanced sonography (CEUS) examination permits identification of hemangioma of the liver in most cases. This method is particularly useful when the ultrasound pattern is atypical on standard grayscale examination. CEUS appearances suggestive of hemangioma are peripheral globular enhancement, progression of enhancement toward the center of the nodule, and persistence of enhancement in the late phase. We present seven cases of hemangioma, which were atypical on CEUS examination due to washout during the portal and late phases, resulting in a hypoenhanced appearance compared with the adjacent liver parenchyma. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound41:361–365, 2013

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