The relationship between exposure to combat stressors and poorer postdeployment health is well documented. Still, some individuals are more psychologically resilient to such outcomes than others. Researchers have sought to identify the factors that contribute to resilience in order to inform resilience-building interventions. The present study assessed the criterion validity of a model of psychological resilience composed of various intrapersonal and interpersonal variables for predicting mental health among Canadian Forces (CF) members returning from overseas deployment. Participants included 1,584 male CF members who were deployed in support of the mission in Afghanistan between 2008 and 2010. Data on combat experiences and mental health collected through routine postdeployment screening were linked with historical data on the intrapersonal and interpersonal variables from the model. The direct and moderating effects of these variables were assessed using multiple linear regression analyses. Analyses revealed direct effects of only some intrapersonal and interpersonal resilience variables, and provided limited support for moderating effects. Specifically, results emphasized the protective nature of conscientiousness, emotional stability, and positive social interactions. However, other variables demonstrated unexpected negative associations with postdeployment mental health (e.g., positive affect and affectionate social support). Ultimately, results highlight the complexities of resilience, the limitations of previous cross-sectional research on resilience, and potential targets for resilience-building interventions. Additional longitudinal research on the stability of resilience is recommended to build a better understanding of how resilience processes may change over time and contribute to mental health after adverse experiences.