Necrotising, proliferative glomerulonephritis due to monoclonal cryoglobulinaemia

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Renal involvement is uncommon in the rare condition of Type I cryoglobulinaemia. On review of the literature most cases featured membranoproliferative glomerulonephritis on renal biopsy. In this case report, we describe a presentation of rapidly progressive glomerulonephritis that histologically demonstrated necrotising, proliferative glomerulonephritis. Treatment with a cytotoxic agent and corticosteroids has resulted in clinical stability.

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