Nail-Patella Syndrome: Pathogenesis, Clinical Features, and Management

    loading  Checking for direct PDF access through Ovid

Abstract

Nail-patella syndrome (NPS) is an autosomal-dominant dysmorphic disorder that occurs in an estimated 1 of every 50,000 individuals. The most common clinical findings are a hypoplastic patella, elbow dysplasia, iliac horns, and hypoplastic nails. Because renal and ophthalmologic complications are prevalent, the management of NPS is multidisciplinary. Patellar abnormalities are the primary focus of orthopaedic management, while the remaining clinical features are most commonly managed nonoperatively.

Related Topics

    loading  Loading Related Articles