Most digital prosthesis designs consider only the maximal intercuspal position (MIP) and not the lateral movement. During the computer-aided design and computer-aided manufacture (CAD-CAM) prosthesis delivery process, the clinician has to adjust the prosthesis to avoid occlusal interference during lateral excursion. The novel digital workflow described in this report can be divided into 2 steps. After obtaining interocclusal records for the MIP and the lateral excursion position, the crown CAD data were designed using a general digital workflow considering only the MIP. The previous crown CAD data were then adjusted in the lateral excursion state before manufacturing the prosthesis. This process using information for 2 occlusal positions means that the definitive prosthesis design reflects not only static occlusion but also lateral mandibular relation.