Validation of Clinical Indicators of the Nursing Diagnosis of Ineffective Protection in Adolescents With Cancer

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Purpose:To validate the clinical indicators of the nursing diagnosis of Ineffective protection in adolescents with cancer based on diagnostic accuracy measurements.Design and Methods:Measurements of sensitivity and specificity for the indicators were calculated using latent class analysis with random effects in a sample of 127 adolescents between 10 and 19 years of age.Results:The prevalence of diagnosis was estimated at 93.7%. The indicators deficient immunity and weakness showed higher sensitivity values, whereas opportunistic infections, recurrent infections, insomnia, mucosal lesions, and coughing showed high specificity.Conclusions:Seven indicators were clinically validated.Practice Implications:The validation of clinical indicators provides nurses with the knowledge of useful signs and symptoms to identify early spectra of a nursing diagnosis or confirm their presence in a specific population. In clinical practice, this knowledge contributes to an accurate diagnostic inference and the planning of nursing interventions directed to the idiosyncrasies of individuals.Highlights:The study clinically validates the indicators of nursing diagnosis Ineffective protection in adolescents with cancer.Seven clinical indicators presented better measures of accuracy, according to a latent class analysis with random effects.Some differences were observed in measures of accuracy in latent class models adjusted for specifics groups.

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