Journal of Pediatric Hematology/Oncology. 40(3):235–237, APR 2018

DOI: 10.1097/MPH.0000000000000993

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PMID: 29557917

Issn Print: 1077-4114

Publication Date: 2018/04/01


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Concurrent Acute Myelofibrosis and Acute Lymphoblastic Leukemia in Childhood: Case Report and Review of the Literature

Waltraud Friesenbichler;Angela Schumich;Ingrid Simonitsch-Klupp;Renate Panzer-Grümayer;Oskar Haas;Georg Mann;Michael Dworzak;

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Abstract

Myelofibrosis is associated with a wide variety of neoplastic and non-neoplastic bone marrow diseases, predominately myeloproliferative neoplasms and acute myeloid leukemia. The following case documents an unusual patient presenting with pancytopenia and acute myelofibrosis accompanied by precursor B-cell acute lymphoblastic leukemia. This very rare clinical presentation raises questions concerning the relationship between concurrent occurrence of acute myelofibrosis and acute lymphoblastic leukemia.

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