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The coincidence timing resolution is a critical parameter for triple coincidence to measure the three photon positron annihilation yield. The yield is inversely proportional to the concentration of oxygen which acts as a quenching agent within the tissue and, therefore, provides important information about the state of the cancerous tumor. A comparison between scintillation and semiconductor detectors with respect to their timing properties for triple coincidence measurements and imaging was carried out. The coincidence timing resolution for example for HPGe detectors was found to vary between 35.4±0.02 and 42.8±0.02 ns. A comparison of all detector characteristics with respect to HPGe is presented.