Significant therapeutic advances for soft tissue sarcomas allow increasing numbers of patients—adult and pediatric—to achieve long term survival. However, the harsh cytotoxic therapies are responsible for adverse physical and psychosocial effects that require long-term follow-up care, specific to survivorship issues. In the adult and pediatric patient population, guidelines for care developed by experts in comprehensive survivorship clinics are evolving to assist the practitioner while on-line supports bring information directly to the survivors. J. Surg. Oncol. 2015 111:648–655. © 2014 Wiley Periodicals, Inc.