Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery

    loading  Checking for direct PDF access through Ovid

Abstract

Lumbo-sacral chordoma is a rare, slow-growing tumor, arising from embryonic nothocordal remnants. Wide en bloc excision with clear margins remains mandatory to achieve satisfactory recurrence rates and disease-free survival. No chemotherapy has been demonstrated to be effective and radiotherapy is only marginally effective. Tyrosine kinase receptor inhibitors have showed encouraging results in locally advanced and metastatic chordoma. Reconstructive surgery may become very complex. Multidisciplinary approach in tertiary hospitals is always necessary. J. Surg. Oncol. 2015; 112:544–554. © 2015 Wiley Periodicals, Inc.

Related Topics

    loading  Loading Related Articles