Persistent Intracranial Hypertension Treated by Hypothermic Therapy After Severe Head Injury Might Induce Late-Phase Cerebral Vasospasm

    loading  Checking for direct PDF access through Ovid



Vasospasm caused by intracranial hypertension in head injury remains controversial.


Between 1996 and 2004, we prospectively and consecutively performed conventional cerebral angiography for six patients with head injuries who showed persistent intracranial hypertension (over 20 mm Hg for longer than 5 days) despite performing various treatments for intracranial hypertension.


All subjects had a minor hemorrhage at admission, classified as Fisher group 2. Five of the six patients had angiographically confirmed vasospasm, and one of them later developed a cerebral infarction. Four of the five subjects who exhibited cerebral vasospasm had undergone hypothermic therapy to control the intracranial hypertension.


Our results suggest that persistent intracranial hypertension that is treated by hypothermic therapy may be related to late phase cerebral vasospasm.

Related Topics

    loading  Loading Related Articles